Enzyme activity measurements using bio-layer interferometry
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United States of America Patent
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Nov 4, 2008
Grant Date -
Jul 13, 2006
app pub date -
Jan 6, 2006
filing date -
Jan 7, 2005
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Abstract
Disclosed are enzyme assays using biolayer interferometry. Assays may be carried out using immobilized substrate or with a substrate capture format. In certain embodiments, the assays are carried out using unlabeled substrates. The methods are broadly applicable to enzyme assay measurements, can be carried out in vivo or in vitro, and are easily multiplexed.
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