Infectious bronchitis virus with an altered spike gene
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United States of America Patent
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Nov 4, 2008
Grant Date -
Jul 5, 2007
app pub date -
Mar 3, 2004
filing date -
Mar 3, 2003
priority date (Note) -
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Abstract
The present invention provides a vaccine for use in the protection of poultry against infectious bronchitis comprising an attenuated infectious bronchitis virus (IBV) and a pharmaceutical acceptable carrier or diluent, characterized in that the attenuated IBV comprises a heterologous spike gene. Such a vaccine is based on IBV strain Beaudette that is able to express a spike gone derived from a different IBV strain. The vaccines provided by the present invention also allow the administration via the in ovo route.
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