Biomaterials modified with superoxide dismutase mimics
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United States of America Patent
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Nov 4, 2008
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N/A
app pub date -
May 26, 2000
filing date -
May 27, 1999
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Expired
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Abstract
The present invention relates to biomaterials modified with non-proteinaceous catalysts for the dismutation of superoxide, and processes for making such materials. This modification may be by covalent conjugation, copolymerization, or admixture of the non-proteinaceous catalysts with the biomaterial. The resulting modified biomaterials exhibit a marked decrease in inflammatory response and subsequent degradation when placed in contact with vertebrate biological systems.
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