Thiazole derivatives
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United States of America Patent
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Oct 28, 2008
Grant Date -
Dec 7, 2006
app pub date -
Aug 17, 2006
filing date -
Jan 27, 2003
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A compound of the formula (I): R.sup.1--NH--X--Y-Z (I) wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof useful as a vascular adhesion protein-1 (VAP-1) inhibitor, a pharmaceutical composition, a method for preventing or treating a VAP-1 associated disease, especially macular edema, which method includes administering an effective amount of the compound or a pharmaceutically acceptable salt thereof to a mammal, and the like.
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