Selection system
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United States of America Patent
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Oct 28, 2008
Grant Date -
N/A
app pub date -
Nov 10, 2000
filing date -
May 13, 1998
priority date (Note) -
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Abstract
The present invention concerns a method for the selection of a virus comprising the steps of: (a) providing a virus encoding and displaying a fusion polypeptide, said fusion polypeptide comprising a heterologous polypeptide inserted into the sequence of a viral coat protein polypeptide, wherein said virus comprises a cleavable site located within a displayed polypeptide; (b) exposing the virus to a cleaving agent; (c) propagating the virus comprising intact fusion protein.
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