Polypeptide having an activity to support proliferation or survival of hematopoietic stem or progenitor cells
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United States of America Patent
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Oct 21, 2008
Grant Date -
Nov 17, 2005
app pub date -
Apr 25, 2003
filing date -
Apr 26, 2002
priority date (Note) -
Expired
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Abstract
A gene encoding a polypeptide having an activity to support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is isolated by comparing expressed genes between cells which support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells and cells which do not support the proliferation or survival. Proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is supported by using stromal cells in which the isolated gene is expressed or a gene product of the isolated gene.
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