Cripto tumour polypeptide
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United States of America Patent
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Oct 21, 2008
Grant Date -
Mar 18, 2004
app pub date -
Aug 20, 2001
filing date -
Aug 24, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Compositions and methods for the therapy and diagnosis of cancer, particularly lung, colon, colorectal and breast cancer, are disclosed. Illustrative compositions comprise one or more Cripto tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung, colon, colorectal and breast cancer.
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