Humanized anti-VLA4 immunoglobulins
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United States of America Patent
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Oct 14, 2008
Grant Date -
May 25, 2006
app pub date -
Dec 8, 2004
filing date -
Jan 25, 1994
priority date (Note) -
Expired
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Abstract
The invention provides methods of treatment using humanized immunoglobulins that specifically bind to alpha-4 integrin. The methods are useful for treatment of asthma, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, transplant rejection, graft versus host disease, tumor metastasis, nephritis, atopic dermatitis, psoriasis, myocardial ischemia, and acute leukocyte mediated lung injury.
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