Pyridine derivatives
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United States of America Patent
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Oct 14, 2008
Grant Date -
Sep 14, 2006
app pub date -
Sep 30, 2005
filing date -
Sep 22, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Pyrimidine compounds of general formula: ##STR00001## wherein --R.sup.1 represents ##STR00002## in which R.sup.11 is hydrogen, C.sub.1-6 alkyl, halogen, hydroxy, C.sub.1-12 alkoxy, nitro, amino, C.sub.1-6 alkylsulfonylamino, C.sub.1-6 alkoxycarbonyl, C.sub.1-6 alkylamino, di (C.sub.1-6 alkyl)amino, C.sub.1-6 alkanoylamino, phenyl C.sub.1-6 alkylamino, phenylsulfonylamino, or --O--(CH.sub.2).sub.n--R.sup.111; R.sup.2 represents hydrogen or halogen; R.sup.3 represents hydrogen, --CR.sup.31R.sup.32R.sup.33; R.sup.4 is hydrogen, carbamoyl, CN, carboxyl, etc.; R.sup.5 is amino, C.sub.1-6 alkylamino, di C.sub.1-6 alkylamino, etc. or salt thereof. The compound has an excellent anti-inflammatory activity, and other biological activity.
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