Antibodies to VEGF-C

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United States of America Patent

PATENT NO 7423125
APP PUB NO 20040147726A1
SERIAL NO

10792461

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Abstract

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Provided are purified and isolated VEGF-C polypeptides capable of binding to at least one of KDR receptor tyrosine kinase (VEGFR-2) and Flt4 receptor tyrosine kinase (VEGFR-3); analogs of such peptides that have VEGF-C-like or VEGF-like biological activities or that are VEGF or VEGF-C inhibitors; polynucleotides encoding the polypeptides; vectors and host cells that embody the polynucleotides; pharmaceutical compositions and diagnostic reagents comprising the polypeptides; and methods of making and using the polypeptides.

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Patent Owner(s)

Patent OwnerAddress
VEGENICS LIMITEDTOORAK VICTORIA 3142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alitalo, Kari Helsinki, FI 130 1966
Joukov, Vladimir Boston, MA 18 637

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