N-terminal and C-terminal markers in nascent proteins

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United States of America Patent

PATENT NO 7423122
APP PUB NO 20060068449A1
SERIAL NO

10993568

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Abstract

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This invention relates to non-radioactive markers that facilitate the detection and analysis of nascent proteins translated within cellular or cell-free translation systems. Nascent proteins containing these markers can be rapidly and efficiently detected, isolated and analyzed without the handling and disposal problems associated with radioactive reagents. Methods are described for incorporating N-terminal, C-terminal and (optionally) affinity markers into a nascent protein

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Patent Owner(s)

Patent OwnerAddress
AMBERGEN INC44 MANNING ROAD SUITE 105 BILLERICA MA 01821

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gite, Sadanand Cambridge, MA 20 208
Olejnik, Jerzy Brookline, MA 108 1475
Rothschild, Kenneth J Newton, MA 103 1574

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