4-6-diphenyl pyridine derivatives as antiinflammatory agents
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United States of America Patent
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Aug 12, 2008
Grant Date -
May 20, 2004
app pub date -
Nov 19, 2001
filing date -
Dec 1, 2000
priority date (Note) -
Expired
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Abstract
4-aryl pyrimidine compounds of general formula and salts thereof: wherein X is CH or N; R1 is hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, etc.; R2 is hydrogen or hydroxy; R3 is hydrogen, C1-6 alkyl, etc.; R4 is hydrogen, hydroxy, halogen, amino, etc.; R5 is hydroxy, amino, carboxy, etc.; R6 is hydrogen, carbamoyl, cyano, carboxy, C1-6 alkoxycarbonyl, etc. and R7 is amino or C1-6 alkanoylamino. The compounds (I) or the salts thereof have an excellent anti-inflammatory activity and the like.
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