Pyruvate producing yeast strain
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United States of America Patent
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Jul 29, 2008
Grant Date -
Mar 17, 2005
app pub date -
Apr 29, 2004
filing date -
May 2, 2003
priority date (Note) -
Expired
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Abstract
Disclosed herein are glucose tolerant C.sub.2 carbon source-independent (GCSI) yeast strains having no detectable amount of pyruvate decarboxylase activity, wherein wild type yeast strains for the glucose tolerant C.sub.2 carbon source-independent yeast strains are Crabtree positive. Also disclosed are methods of selecting glucose tolerant C.sub.2 carbon source-dependent yeast strains, and methods of producing pyruvic acid or salts thereof using glucose tolerant C.sub.2 carbon source-independent yeast strain. Further disclosed herein are GCSI yeast strains having a genome that comprises an exogenous lactate dehydrogenase gene.
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