Method and device for analyzing the intracellular chemical state of living cells by nuclear magnetic resonance
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United States of America Patent
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Jul 22, 2008
Grant Date -
Oct 23, 2003
app pub date -
Oct 12, 2001
filing date -
Oct 13, 2000
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Abstract
The invention concerns a method for analysing the intracellular chemical state of living cells by nuclear magnetic resonance (NMR). Said method comprises a step which consists in preparing the cell sample and a step which consists in an NMR analysis of the sample, both steps being carried out at very low temperature so as to freeze the biochemical state of the living cells to obtain specific and accurate reproducible measurements of the cellular functioning in given conditions. The invention also concerns the device coupled to the NMR spectrometer for implementing the method of analysis.
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