Placental organic anion transporter and gene thereof
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United States of America Patent
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Jul 1, 2008
Grant Date -
May 22, 2003
app pub date -
Jan 9, 2003
filing date -
Jul 1, 1999
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Abstract
A novel organic anion transporter gene participating in organic anion transport in the placenta; and an organic anion transporter which is a polypeptide encoded by the gene. A placental organic anion transporter OAT4, more particularly, a placental organic anion transporter OAT4 having the amino acid sequence represented by SEQ ID NO:2 or an amino acid sequence derived therefrom by deletion, substitution or addition of a part of the amino acids thereof. A nucleic acid (preferably DNA) having a base sequence encoding the placental organic anion transporter OAT4 or a base sequence hybridizable therewith under stringent conditions.
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