Methods and compounds for inhibiting amyloid deposits

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United States of America Patent

PATENT NO 7393875
APP PUB NO 20040248876A1
SERIAL NO

10429198

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Abstract

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Methods and compositions which are useful in the treatment of amyloidosis. In particular, methods and compositions are provided for inhibiting, preventing and treating amyloid deposition, e.g., in pancreatic islets, wherein the amyloidotic deposits are islet amyloid polypeptide (IAPP)-associated amyloid deposition or deposits. The methods of the invention involve administering to a subject a therapeutic compound which inhibits IAPP-associated amyloid deposits. Accordingly, the compositions and methods of the invention are useful for inhibiting IAPP-associated amyloidosis in disorders in which such amyloid deposition occurs, such as diabetes.

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Patent Owner(s)

Patent OwnerAddress
BELLUS HEALTH (INTERNATIONAL) LIMITEDFEDERAL POLYTECHNICAL SCHOOL AT LAUSANNE SCIENCE PARK LAUSANNE CH-1015

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gupta, Ajay Pointe-Claire, CA 233 4450
Kong, Xianqi Dollard-des-Ormeaux, CA 84 724
Migneault, David Laval, CA 25 291
Szarek, Walter A Kingston, CA 24 282
Weaver, Donald F Kingston, CA 33 470

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