Use of substituted 8-Perfluoroalkyl-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives as therapeutic agents
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United States of America Patent
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Jul 1, 2008
Grant Date -
Aug 16, 2007
app pub date -
Apr 4, 2007
filing date -
Mar 21, 2003
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention relates to use of a substituted-pyrimidone derivative represented by formula (I) or a salt thereof: ##STR00001## wherein X, Y, R1, R2, R3, R4, R5, n, p and q are as described herein for treating a variety of disease states. More specifically, the invention relates to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a disease caused by abnormal activity of GSK3.beta., such as Pick's disease.
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