Compositions derived from Modiolus modiolus and methods for making and using same
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United States of America Patent
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Jun 17, 2008
Issued Date -
N/A
app pub date -
Mar 22, 2001
filing date -
Mar 22, 2000
priority date (Note) -
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Abstract
Disclosed are compositions which include an isolated soft tissue from Modiolus modiolus ('MM') and compositions which include an oil isolated from MM or a portion thereof. Also disclosed are methods of treating adenocarcinoma in a subject; methods of decreasing proliferation of adenocarcinoma cells, or of inducing apoptosis of adenocarcinoma cells, or of inducing differentiation of adenocarcinoma cells into non-cancerous cells; methods of inhibiting the activity of 5-lipoxygenase or 12-lipoxygenase or both in cells; and methods of treating a subject suffering from a disease or condition associated with excessive 5-lipoxygenase activity or 12-lipoxygenase activity or both. A process for preparing an MM extract by contacting MM or a portion thereof with a solvent under conditions effective to extract one or more materials from the MM or portion thereof is also described.
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