Homogeneous multiplex screening assays and kits
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United States of America Patent
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Jun 10, 2008
Grant Date -
May 29, 2008
app pub date -
Apr 30, 2003
filing date -
Apr 30, 2003
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Abstract
Highly multiplexed homogeneous in vitro screening assays for numerous possible nucleic acid targets, any of which might be present in a sample, utilize fluorescent hybridization probes that are combinatorially coded from a panel of fluorophores by subdividing each probe into portions and differently labeling each portion such that, when portions are combined, each probe has a unique code. The assays may include target amplification and real-time detection. Probe sets and kits containing additional assay reagents may be used to perform the screening assays.
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