9-amino-podophyllotoxin derivatives, method for the production thereof and pharmaceutical compositions containing said derivatives
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United States of America Patent
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May 27, 2008
Grant Date -
Nov 2, 2006
app pub date -
Sep 1, 2004
filing date -
Sep 2, 2003
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention relates to compounds of formula (I), wherein R.sub.1 is a group selected from hydrogen, alkyl, aryl, aryalkil, heteroaryl, heteroarylalkyl, alkylcarbonyl, arylcarbonyl, arylalkylcarbonyl, alkoxycarbonyl, aryloxycarbonyl, arylalkoxycarbonyl, heterocycloalkoxycarbonyl, alkylsulfonyl, arylsulfonyl, arylalkylsulfonyl, phosphonic and Si(Ra).sub.2R.sub.b, Y is a group selected from HN--NH and N--R.sub.2, R.sub.3 is a hydrogen atom, an alkyl, cycloalkyl, aryl, arylalkyl group, R.sub.4 is hydrogen atom or an alkyl group, enantiomers, diastereoisomers and the salts thereof ##STR00001##
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