Reaction monitoring of chiral molecules using fourier transform infrared vibrational circular dichroism spectroscopy

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United States of America Patent

PATENT NO 7378283
APP PUB NO 20060009919A1
SERIAL NO

10685319

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Abstract

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A method and apparatus to monitor the enantiomeric excess of chiral molecules participating in a chemical reaction. The method includes real time monitoring of the chemical reaction by obtaining a VCD spectra and an IR spectra of the chemical compounds in the reaction, and manipulating the spectra to obtain a % EE value. Using such real time information, the reaction parameters can be changed to shift the reaction to produce more of one chiral molecule than another.

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BIOTOOLS INC17546 SR 710 BEELINE HWY JUPITER FL 33458

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dukor, Rina K Lake Zurion, IL 4 296
Guo, Changning Syracuse, NY 1 1
Nafie, Laurence A Claero, NY 3 13

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