Alkyl-linked nucleotide compositions
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United States of America Patent
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May 13, 2008
Grant Date -
Oct 28, 2004
app pub date -
Jan 21, 2004
filing date -
Jan 22, 2003
priority date (Note) -
Expired
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Abstract
Alkyl-linked nucleotide non-homogeneous solid supports and nucleotide affinity media comprising an alkyl-linked nucleotide are provided. The linker is generally a hydrophobic linker that can be a 3, 4, 5, 6, 7, 8, 9, 10, or a longer carbon chain. Also included in the invention are methods for synthesis of an alkyl-linked nucleotide, nucleotide affinity media and methods of use thereof for affinity chromatography and screening methods.
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