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Abstract

An 1-amido-3-(2-hydroxyphenoxy)-2-propanol derivative represented by the following formula (1), ##STR00001## wherein cycle A may have further 1 to 4 substituents, and said substituent means a substituent selected from the group consisting of saturated or unsaturated C1-4 alkyl group, aralkyl group in which alkyl moiety has 1 to 4 carbon atoms, aryl group, halogen atom, halogenated C1-4 alkyl group, C2-5 alkanoyl group, mono or dialkylcarbamoyl group in which alkyl moiety has 1 to 4 carbon atoms, cyano group and nitro group, and the substituents at positions 3 and 6, or at positions 4 and 5 on the cycle A are different each other. Other ring may be fused at positions 3 and 4, or at positions 5 and 6 on the cycle A to form a condensed polycyclic hydrocarbon with the cycle A. R.sup.1 is alkanoyl group or aroyl group, and R.sup.2 is hydrogen atom, alkanoyl group or aroyl group, or R.sup.1 and R.sup.2 may be combined together with the N atom to form a cyclic imido group, which is useful as an intermediate of medicines, etc.

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First Claim