Quinazolinone compounds with reduced bioaccumulation
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United States of America Patent
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May 6, 2008
Grant Date -
Sep 1, 2005
app pub date -
Nov 19, 2004
filing date -
Nov 19, 2003
priority date (Note) -
Expired
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Abstract
A variety of small molecule, guanidine-containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the formula IA and IB. IA and IB have the following structures where Z has the formula shown below and the rest of the variables are defined herein ##STR00001##
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