Gene functionally related to dyslexia
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United States of America Patent
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Apr 8, 2008
Grant Date -
Jul 15, 2004
app pub date -
Oct 9, 2003
filing date -
Feb 12, 2002
priority date (Note) -
Expired
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Abstract
The present invention describes a novel human gene, DYXC1, which is functionally related to dyslexia. DYXC1 gene encodes a 420-amino acid residue protein. DYXC1 is expressed in several tissues, including the brain, and is localized in the nucleus. In addition, four single nucleotide polymorphisms (SNPs) in DYXC1 mRNA have been characterized in this invention. The invention provides diagnostic methods and materials for analysing allelic variation in DYXC1 gene. This invention also provides polypeptides encoded by DYXC1 gene and antibodies binding to said polypeptides.
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