Substituted anilide ligands for the thyroid receptor
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United States of America Patent
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Mar 11, 2008
Grant Date -
Sep 16, 2004
app pub date -
Jan 23, 2004
filing date -
Jan 24, 2003
priority date (Note) -
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Abstract
Novel thyroid receptor ligands are provided having the general formula I ##STR00001## wherein X, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10, R.sub.11, R.sub.12 and R.sub.13 are as defined herein. In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolic dysfunction or which are dependent upon the expression of a T.sub.3 regulated gene, wherein a compound as described above is administered in a therapeutically effective amount.
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