Human antihuman MCP-1 antibody and antibody fragment thereof
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United States of America Patent
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Mar 11, 2008
Grant Date -
Nov 2, 2006
app pub date -
Sep 10, 2003
filing date -
Sep 12, 2002
priority date (Note) -
Expired
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Abstract
A substance effective for treating immunopathy where MCP-1 is involved is provided. scFv having a high affinity to human MCP-1 was obtained using phage antibody technique. Based on information of VH chain and VL chain obtained from said scFv, a human anti-human MCP-1 antibody and a human anti-human MCP-1 antibody fragment are obtained. Said antibody and antibody fragment are expected to be useful as a medicament for treating inflammation and immunopathy caused by MCP-1.
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