Therapeutic targets for treatment of HCV infections, methods of treating HCV infections and compounds useful therefor
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United States of America Patent
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Mar 11, 2008
Grant Date -
Aug 5, 2004
app pub date -
Nov 26, 2003
filing date -
Apr 13, 2001
priority date (Note) -
Expired
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Abstract
The present invention relates to the human cellular protein glutathione peroxidase-gastrointestinal as a target for medical intervention against Hepatitis C virus (HCV) infections. Furthermore, the present invention relates to a method for the detection of compounds useful for prophylaxis and/or treatment of Hepatitis C virus infections and a method for detecting Hepatitis C virus infections in an individual or in cells. Also compositions, compounds, nucleic acid molecules (such as aptamers), mono-or polyclonal antibodies are disclosed which are effective for the treatment of HCV infections, and methods for prophylaxis and/or treatment of Hepatitis C virus infections or for the regulation of Hepatitis C virus production are disclosed.
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