Heterocycle substituted carboxylic acids
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United States of America Patent
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Feb 12, 2008
Grant Date -
Jan 6, 2005
app pub date -
Apr 30, 2004
filing date -
Apr 30, 2003
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
The present invention relates to compounds and pharmaceutically acceptable salts of formula (I): ##STR00001## which are useful in the treatment of metabolic disorders related to insulin resistance, leptin resistance, or hyperglycemia.Compounds of the invention include inhibitors of Protein tyrosine phosphatases, in particular Protein tyrosine phosphatase-1B (PTP-1B), that are useful in the treatment of diabetes and other PTP mediated diseases, such as cancer, neurodegenerative diseases and the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds.
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Cited Art Landscape
Patent Citation Ranking
- 1 Citation Count
- C07D Class
- 21.95 % this patent is cited more than
- 17 Age
