Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases

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United States of America Patent

PATENT NO 7329650
APP PUB NO 20050282754A1
SERIAL NO

11184459

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Abstract

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The present invention relates to peptides and peptide analogues designed from HFE protein. In particular, it relates to peptides and peptide analogues designed from an alpha-1 region of HFE protein which lowers the binding affinity of transferrin receptor for transferrin. Such compounds mimic HFE protein function, and reduce iron uptake and/or accumulation by a cell.

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Patent Owner(s)

Patent OwnerAddress
BIO-RAD LABORATORIES INCCALIFORNIA USA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennett, Melanie Pasadena, CA 3 13
Bjorkman, Pamela J Pasadena, CA 44 227
Feder, John N San Carlos, CA 150 988
Lebron, Jose Pasadena, CA 4 13
Schatzman, Randall C Daly City, CA 16 205

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