Analogs of gastric inhibitory polypeptide and their use of treatment for diabetes
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United States of America Patent
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Feb 5, 2008
Grant Date -
Dec 15, 2005
app pub date -
Mar 25, 2005
filing date -
Mar 29, 1999
priority date (Note) -
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Abstract
The present invention provides peptides which stimulate the release of insulin. The peptides, based on GIP 1-42 include substitutions and/or modifications which enhance and influence secretion and/or have enhanced resistance to degradation. The invention also provides a process of N terminally modifying GIP and the use of the peptide analogues for treatment of diabetes.
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