Immunogenicity of glucan binding protein
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United States of America Patent
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Jan 29, 2008
Grant Date -
Jul 1, 2004
app pub date -
Mar 7, 2003
filing date -
Mar 7, 2002
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Abstract
Immunogenic compositions and subunit vaccines for dental caries are described which comprise peptide subunits of glucan binding protein-B and peptide subunits of glucan binding protein-B in combination with peptide subunits of glucosyltransferase. Methods of provoking an immune response to S. mutans glucan binding protein-B or glucosyltransferase. Methods of immunizing a mammal against dental caries are also described, along with antibodies which bind particular epitopes of glucan binding protein-B or glucosyltransferase.
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