Synergistic antimicrobial compositions and methods of inhibiting biofilm formation
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United States of America Patent
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Jan 1, 2008
Grant Date -
Mar 3, 2005
app pub date -
Feb 17, 2004
filing date -
Aug 25, 2003
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Abstract
A synergistic antimicrobial composition for inhibiting biofilm formation includes an iron-sequestering glycoprotein, a cationic polypeptide and a chelating agent, or an iron-sequestering glycoprotein and a chelating agent, or an iron-sequestering glycoprotein and a cationic polypeptide. Additionally, surfactants and quaternary ammonium compounds may also be advantageously combined with iron-sequestering glycoproteins in an antimicrobial composition. Methods of using a synergistic composition for inhibiting medical device biofilm formation are also disclosed.
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