Nucleic acids associated with rheumatoid arthritis, and methods and kits for the diagnosis thereof
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United States of America Patent
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Dec 11, 2007
Grant Date -
Jan 22, 2004
app pub date -
Oct 24, 2001
filing date -
Oct 24, 2000
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Abstract
Mutations in a genome associating in rheumatoid arthritis (RA) are found in human DR3 genomic DNA having the base sequence represented by SEQ ID NO:1. The invention provides a genome having such mutations, transcripts thereof, a method of highly accurately evaluating the RA onset or the RA onset possibility by using the mutations thereof, an evaluation kit therefor, and a therapeutic method and remedies for RA.
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