Mammalian MDM2 binding proteins
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United States of America Patent
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Dec 4, 2007
Grant Date -
Jun 7, 2007
app pub date -
Jan 5, 2007
filing date -
Jul 12, 2000
priority date (Note) -
Expired
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Abstract
Isolated nucleic acid sequences encoding mammalian MDM2 binding protein and polypeptide sequences for the mammalian MDM2 binding protein are provided. Also provided are vectors containing these nucleic acid sequences, host cells which express these proteins and antibodies targeted to these proteins. In addition, methods and compositions for modulating the G.sub.1 phase of the cell cycle via altering expression and/or activity of a mammalian MDM2 binding protein are provided.
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