3-amido-1,2-benzoisoxazole derivatives, process for preparation, and use thereof
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United States of America Patent
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Nov 6, 2007
Grant Date -
Jan 27, 2005
app pub date -
Nov 5, 2002
filing date -
Nov 6, 2001
priority date (Note) -
Expired
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Abstract
The present invention relates to 3-amido-1,2-benzoisoxazole derivatives and their salts represented by formula 1, processes for preparation and usees thereof. More particularly, it relates to a method for improving its bioavailability introducing amino acid residue to the amine group of a 3-amido-1,2-benzoisoxazole. The compounds according to the present invention are used as an antagonist against Leukotriene-B-4 receptor, an inhibitor or therapeutics of osteoroposis, thus inhibiting osteolysis and stimulating osteogensis.
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