Substituted biaryl amides C5a receptor modulators
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United States of America Patent
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Nov 6, 2007
Grant Date -
Aug 10, 2006
app pub date -
Jan 3, 2006
filing date -
Mar 28, 2002
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Expired
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Abstract
Substituted biaryl amides of Formula I are provided. Such compounds are ligands that may be used to modulate C5a receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological C5a receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies ##STR00001##
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