Methods for identifying active compounds
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United States of America Patent
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Oct 23, 2007
Grant Date -
Feb 24, 2005
app pub date -
Jun 28, 2004
filing date -
Jun 30, 2003
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to methods for identifying agents that modulate the effect of cytokine class I receptor binding compounds, by inhibiting the interaction between the cytokine class I receptor and nuclear factors. The agents are useful for decreasing IGF-1 levels in a cell, and for the treatment of medical disorders caused by hormone dysregulation, such as growth hormone or prolactin dysregulation.
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