Imidazo-pyrimidines and triazolo-pyrimidines: benzodiazepine receptor ligands
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Sep 18, 2007
Grant Date -
Feb 17, 2005
app pub date -
Jul 23, 2004
filing date -
Jul 25, 2003
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
Compounds of Formula I ##STR00001## are provided, as are methods for their preparation. The variables Z.sub.1, Z.sub.2, Z.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8 and Ar in the above formula are defined herein. Such compounds may be used to modulate ligand binding to GABA.sub.A receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) disorders in humans, domesticated companion animals and livestock animals. Compounds provided herein may be administered alone or in combination with one or more other CNS agents to potentiate the effects of the other CNS agent(s). Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting GABA.sub.A receptors (e.g., receptor localization studies).
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully