Antibiotics, tripropeptins and process for producing the same

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United States of America Patent

PATENT NO 7271147
APP PUB NO 20030162697A1
SERIAL NO

10239324

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Abstract

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By culturing Lysobacter sp. BMK333-48F3 (deposit number of FERM BP-7477), an antibiotic, tripropeptin Z, tripropeptin A, tripropeptin B, tripropeptin C or tripropeptin D represented by the general formula (I): ##STR00001## wherein R is 7-methyl-octyl group, 8-methyl-nonyl group, 9-methyl-dodecyl group, 10-methyl-undecyl group or 11-methyl-dodecyl group, is obtained as antibiotics having excellent antibacterial activities against bacteria and having a novel molecular structure. These tripropeptins each have an excellent antibacterial activity against various bacteria and drug-resistant strains thereof, such as methicillin-resistant strains and vancomycin-resistant strains.

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Patent Owner(s)

Patent OwnerAddress
ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI14-23 KAMI OHSAKI 3-CHOME SHINAGAWA-KU TOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hamada, Masa Tokyo, JP 39 228
Hashizume, Hideki Tokyo, JP 25 214
Igarashi, Masayuki Atsugi, JP 23 27
Naganawa, Hiroshi Tokyo, JP 34 385
Takeuchi, Tomio Tokyo, JP 164 840

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