Substituted stilbene compounds with vascular damaging activity
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United States of America Patent
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Sep 4, 2007
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N/A
app pub date -
Feb 15, 2000
filing date -
Feb 16, 1999
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Expired
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Abstract
A compound for use in inducing necrosis in vascular tissue of a tumor in an animal. The compound contains a first moiety which is a cis-stilbene moiety and a second moiety which is an inhibitor of the formation or action of nitric acid. Also, a method for inducing necrosis in vasculature of a tumor in an animal by administering to the animal the compound in an amount effective for inducing the necrosis.
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