Anti human ovarian cancer-anti CD3 bispecific antibody

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United States of America Patent

PATENT NO 7262276
APP PUB NO 20050255115A1
SERIAL NO

10478345

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Abstract

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The present invention provides an anti-ovarian cancer bispecific antibody. Said antibody includes two polypeptide domains connected by a polypeptide linker, one is anti-ovarian cancer antibody, or its Fab fragment, single complementarity determining region (CDR) antibody or single chain Fv (scFv) and the other is anti-CD3 antibody, or its Fab fragment, single CDR antibody or scFv. The present invention also provides DNA sequences encoding said antibody, an expression vector containing said DNA sequence, and a host cell containing said expression vector.

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Patent Owner(s)

Patent OwnerAddress
INSTITUTE OF GENETICS AND DEVEL BIOL CASBEIJING 100101
DONGGUAN HAOFA BIOTECHNOLOGY DEVELOPMENTAL CO LTD10 XINGYE RD CENTRAL DISTRICT SHATIAN TOWN DONGGNAN GUANGDONG 523980
BEIJING ABT GENETIC ENGINEERING TECNOLOGY CO LTDINSIDE OF INSTITUTE OF GENETICS 917 BLD DATUN RD ANWAI BEIJING 100101

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fang, Min Beijing, CN 103 521
Feng, Jie Beijing, CN 85 1143
Huang, Hualiang Beijing, CN 3 75
Jiang, Xin Beijing, CN 211 2822
Lin, Qing Beijing, CN 49 1001
Yu, Xiaocong Beijing, CN 3 50
Zhou, Ping Beijing, CN 228 1742

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