Neutralizing antibodies against GDF-8 and uses therefor
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United States of America Patent
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Aug 28, 2007
Grant Date -
Jul 22, 2004
app pub date -
Oct 21, 2003
filing date -
Oct 22, 2002
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Abstract
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), in particular human antibodies, and antibody fragments, including those that inhibit GDF-8 activity in vitro and/or in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle or bone, or disorders of insulin metabolism.
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