Human homologue of the DBF4/ASK1 protein, nucleic acids, and methods related to the same

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United States of America Patent

PATENT NO 7259244
APP PUB NO 20040102611A1
SERIAL NO

10311401

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Abstract

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The present invention provides a human polypeptide homolog of DBF4/ASK1 (for 'Activator of S phase kinase') and polynucleotides which identify and encode DRF1 (for 'DBF4 Related Factor 1'). In addition, the invention provides expression vectors, host cells and methods for its production. The invention also provides methods for the identification of DRF1 or DRF1-containing complex agonists/antagonists, useful for the treatment of human diseases and conditions.

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Patent Owner(s)

Patent OwnerAddress
NERVIANO MEDICAL SCIENCES S R LVIALE PASTEUR 10 NERVIANO (MI) 20014

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berthelsen, Jens Milan, IT 2 4
Bosotti, Roberta Nerviano, IT 3 1
Isacchi, Antonella Milan, IT 12 134
Plyte, Simon Milan, IT 4 9

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