Inhibitors of 11-.beta.-hydroxy steroid dehydrogenase type 1
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United States of America Patent
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Aug 7, 2007
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N/A
app pub date -
May 24, 2005
filing date -
May 24, 2004
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Abstract
The present invention relates to compounds with the formula (I), (II), (III) or (IV): ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, X and Z are as defined herein, and also to pharmaceutical compositions comprising the compounds, as well as methods of use of the compounds for treatment of disorders associated with human 11-.beta.-hydroxysteroid dehydrogenase type 1 enzyme and for the preparation of a medicament which acts on the human 11-.beta.-hydroxysteroid dehydrogenase type 1 enzyme.
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