Screening method for a substance having hypoglycemic activity by using STAT-induced inhibitor of STAT function-1
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United States of America Patent
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Jul 24, 2007
Grant Date -
Oct 2, 2003
app pub date -
Sep 11, 2001
filing date -
Sep 11, 2000
priority date (Note) -
Expired
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Abstract
The present invention discloses a screening method for a substance, which could be a therapeutic agent for diabetes with insulin resistance through regulating a function of a molecule involved in insulin signaling pathway. More specifically, the present invention discloses a screening method for a substance having hypoglycemic activity, which is characterized by contacting a sample to STAT-induced inhibitor of STAT function-1 in the presence of insulin, and by detecting inhibitory activity of STAT-induced inhibitor of STAT function-1 by a substance in the sample, as an index.
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