Inhibiting denaturation of nucleic acid duplexes
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United States of America Patent
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Jul 17, 2007
Grant Date -
Aug 21, 2003
app pub date -
Jun 11, 2001
filing date -
Jun 12, 2000
priority date (Note) -
Expired
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Abstract
A solution for treating a nucleic acid duplex having a pH of from 3 to 11, comprising a soluble protein or mixture of proteins; and 0.1 mM to 10 mM divalent cations; wherein the nature and concentration of the protein or mixture of proteins is selected so that the solution is capable of inhibiting heat denaturation of a nucleic acid duplex.
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