Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue

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United States of America Patent

PATENT NO 7241874
APP PUB NO 20040072322A1
SERIAL NO

10606190

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Abstract

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A method for purifying bone-derived osteogenic proteins including a demineralization process, a protein extraction process, a high molecular weight ultrafiltration process, a low molecular weight ultrafiltration process, and a recovery process. The high and low ultrafiltration processes preferably select proteins having a nominal molecular weight between approximately 8 kilodaltons and approximately 50 kilodaltons. Processes of the present invention may be used to recover osteogenic proteins from bone demineralization waste streams.

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Patent Owner(s)

Patent OwnerAddress
ZIMMER ORTHOBIOLOGICS INC12024 VISTA PARKE DRIVE AUSTIN TX 78726

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Thorne, Kevin Austin, TX 9 217

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