Method for treating myolytic disease and method for screening antimyolytic agent

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United States of America Patent

PATENT NO 7238718
APP PUB NO 20050272767A1
SERIAL NO

10919473

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Abstract

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An object of the present invention is to provide a method which is able to prevent or improve the progress of myolytic diseases such as muscular dystrophy. Such an object is able to be solved by a method where an effective dose of an inhibitor for hematopoietic prostaglandin D synthase (H-PGDS) or an antagonist to prostaglandin D receptor is administered to a patient who needs it. The present invention also provides a method for screening compounds which are able to prevent the progress of myolytic diseases and to improve it using human H-PGDS overexpressed transgenic mice.

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Patent Owner(s)

Patent OwnerAddress
OSAKA BIOSCIENCE INSTITUTESUITA-SHI OSAKA 565-0874

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aritake, Kosuke Kawanishi, JP 6 12
Eguchi, Naomi Suita, JP 13 91
Miyano, Masashi Hyogo-ken, JP 13 133
Mori, Ikuko Suita, JP 49 541
Sato, Yo Hyogo-ken, JP 128 1534
Taniike, Masako Itami, JP 3 9
Urade, Yoshihiro Kyoto, JP 29 122

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