Methods of identifying agonists and antagonists of opioid receptors

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United States of America Patent

PATENT NO 7235366
SERIAL NO

08455683

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Abstract

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The invention relates generally to compositions of and methods for obtaining opioid receptor polypeptides. The invention relates as well to polynucleotides encoding opioid receptor polypeptides, the recombinant vectors carrying those sequences, the recombinant host cells including either the sequences or vectors, and recombinant opioid receptor polypeptides. By way of example, the invention discloses the cloning and functional expression of at least three different opioid receptor polypeptides. The invention includes as well, methods for using the isolated, recombinant receptor polypeptides in assays designed to select and improve substances capable of interacting with opioid receptor polypeptides for use in diagnostic, drug design and therapeutic applications.

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Patent Owner(s)

Patent OwnerAddress
ARCH DEVELOPMENT CORPORATION5640 SOUTH ELLIS AVENUE CHICAGO IL 606037

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bell, Graeme I Chicago, IL 19 411
Reisine, Terry Los Angeles, CA 4 3
Yasuda, Kazuki Machida, JP 7 50

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